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Home / Shop / Equipment and Supplies / Professional Microdermabrasion Machines / Nue Skin 100XL Microdermabrasion Machine
Professional Nue Skin 100XL Advanced Microdermabrasion Machine

Nue Skin 100XL Microdermabrasion Machine

Rated 5.00 out of 5 based on 2 customer ratings
(2 customer reviews)

$3,495.00

Nue Skin 100XL professional microdermabrasion machine combines high-performance vacuum with crystals and natural grains for corrective skin resurfacing.

Product Dimensions: 18 inches x 13.5 inches x 9 inches | Product Weight: 25 LBS | Shipping Instructions: Ships into a 20″ x 20″ x 20″ double-walled box. Upon delivery someone 18 years or older must sign for the package.

August Sale! Ends September 7th or until supplies last. Start saving and get ready for the Microdermabrasion Fall/Autumn Season. FREE Shipping.

*All equipment orders placed before 2 PM EST require a 72-hour build time prior to shipping*

*For Licensed Skin Care or Medical Professionals Only*

  • United States (US) dollar ($) - USD
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SKU: NUESKIN100XL Category: Professional Microdermabrasion Machines Tags: aging skin, combination skin, dehydration, dry skin, hyperpigmentation, mature skin, oily skin, sensitive skin, sun damaged skin

Nue Skin 100XL Professional Microdermabrasion Machine

The Nue Skin 100XL Microdermabrasion Machine is a high-performance, two-canister professional resurfacing system designed for estheticians, medical spas, and skincare professionals who want greater treatment versatility and stronger vacuum performance. Its performance motor reaches approximately 27–28 inches/Hg, providing the professional with a broad range of vacuum and exfoliation control for customized treatments.

What separates the Nue Skin 100XL from a conventional crystal microdermabrasion system is its ability to work with both aluminum oxide crystals and natural walnut grains, along with three specialized treatment handpieces—Blue, Red, and Yellow.

Crystal Resurfacing + Natural Grain Polishing

The Nue Skin 100XL gives the skincare professional greater control over how the skin is exfoliated. Aluminum oxide crystals provide controlled mechanical resurfacing for correcting visible texture, while natural walnut grains provide an additional polishing option for developing customized professional treatments.

The two exfoliation media may also be blended to create a dual retexturing and polishing effect. This gives the practitioner additional flexibility when developing protocols for mature and photoaged skin, uneven pigmentation, visible demarcation lines, and post-acne textural irregularities.

Three Handpieces for Greater Treatment Control

The Nue Skin 100XL includes three professional handpieces, each providing a different approach to treatment.

The Blue Handpiece features a four-port ceramic delivery system and is designed for general microdermabrasion application across larger treatment areas.

The Red Handpiece provides a more concentrated delivery for targeted areas where additional resurfacing may be appropriate, including the appearance of deeper lines, post-acne scarring, and localized textural irregularities.

The Yellow Handpiece expands the capabilities of the 100XL by allowing the professional to work with natural grains and customized crystal-and-grain combinations. This makes it possible to transition from traditional crystal resurfacing into a more customized polishing and retexturing treatment.

Adjustable Crystal Flow + Vacuum Performance

Microdermabrasion is not simply about suction. Treatment performance comes from balancing exfoliation media, flow, vacuum pressure, handpiece selection, movement, and the condition of the client’s skin.

The Nue Skin 100XL allows the professional to adjust both crystal flow and vacuum pressure, providing greater control when treating different skin types, colors, sensitivities, and treatment objectives.

Controlled vacuum creates aspiration at the skin’s surface while the selected crystals or grains mechanically exfoliate the stratum corneum. This combination makes the 100XL particularly useful for professionals who want to move beyond basic exfoliation and develop more individualized resurfacing protocols.

Designed for Advanced Esthetic & Clinical Practices

The Nue Skin 100XL is an excellent choice for professionals working with corrective skincare, medical aesthetics, cosmetic dermatology, and laser-based practices where controlled skin resurfacing may be incorporated into a broader treatment program.

Professional microdermabrasion may be used to address the appearance of:

  • Fine lines and wrinkles
  • Photoaged and rough skin
  • Uneven skin texture
  • Post-acne textural irregularities
  • Uneven pigmentation
  • Visible demarcation lines
  • Dull or heavily keratinized skin

For clients undergoing physician-directed treatments, prescription topical therapies, or laser procedures, the timing and appropriateness of microdermabrasion should always be determined according to the client’s medical treatment plan.

One Machine. Multiple Resurfacing Possibilities.

With its 27–28 inches/Hg performance motor, two-canister system, aluminum oxide crystals, natural walnut grains, and Blue, Red, and Yellow professional handpieces, the Nue Skin 100XL gives skincare professionals the ability to move from general exfoliation to targeted resurfacing and customized polishing within one professional system.

The result is greater treatment flexibility for the professional—and a microdermabrasion machine designed to grow with a more advanced treatment menu.

Frequently Asked Questions | Nue Skin 100XL Microdermabrasion Machine

Fact #1 What makes the Nue Skin 100XL different from a standard microdermabrasion machine?

The Nue Skin 100XL is designed for higher-performance corrective esthetic treatments, with a motor capable of reaching approximately 27–28 inches/Hg. This expanded vacuum capability gives experienced professionals greater control when developing protocols for general resurfacing, targeted correction, and more advanced microdermabrasion procedures. The objective is not simply stronger suction—it is having a wider performance range available to customize treatment according to the client’s skin type, condition, treatment area, and tolerance.

Fact #2 Why is the 27–28 inches/Hg motor important for corrective microdermabrasion?

A higher-performance motor provides the vacuum reserve and consistency needed for more advanced professional applications. The esthetician controls the actual treatment pressure rather than automatically operating the machine at maximum vacuum. This allows the Nue Skin 100XL to be adjusted from conservative resurfacing to more focused corrective work while maintaining consistent aspiration and crystal delivery. For an experienced corrective esthetician, that additional performance range provides greater flexibility when treating different areas and skin conditions.

Fact #3 Why is the Nue Skin 100XL well suited for medical spas and cosmetic practices?

The Nue Skin 100XL is designed for corrective estheticians, medical spas, cosmetic dermatology, and aesthetic practices that require greater performance and treatment flexibility. Its high-performance motor, adjustable vacuum and crystal flow allow the practitioner to perform controlled resurfacing ranging from general exfoliation to more focused corrective procedures.

In some medical aesthetic practices, microdermabrasion may also be incorporated as a skin-preparation procedure before selected laser or IPL treatments. Controlled removal of superficial stratum corneum can create a more uniform skin surface as part of a physician-directed treatment protocol.

Because laser and IPL technologies vary considerably in wavelength, treatment depth, indication, and skin response, microdermabrasion should only be performed before these procedures when it is appropriate for the specific device and treatment protocol and has been approved by the supervising or treating medical provider.

This is where the 27–28 inches/Hg performance capability of the Nue Skin 100XL becomes relevant: it provides experienced practitioners with a wider operating range for corrective resurfacing rather than limiting the machine to basic facial exfoliation.

Fact #4 What corrective skin concerns can be addressed with the Nue Skin 100XL?

Professional microdermabrasion can be customized for the appearance of photoaged skin, fine lines and wrinkles, uneven texture, superficial pigmentation, demarcation lines, and post-acne textural irregularities. The Nue Skin 100XL gives the practitioner control over vacuum, exfoliation media, handpiece selection, number of passes, and treatment technique. This makes it especially useful for corrective estheticians who need more treatment flexibility than a basic exfoliation machine provides.

Fact #5 How do the three handpieces, crystals, and natural grains expand the performance of the Nue Skin 100XL?

The Nue Skin 100XL combines its high-performance motor with Blue, Red, and Yellow professional handpieces, aluminum oxide crystals, and natural walnut grains. The Blue handpiece supports general resurfacing, while the Red handpiece provides more concentrated treatment for targeted areas. The Yellow handpiece expands the system into natural-grain treatments and customized crystal-and-grain blending. This allows the corrective esthetician to move between resurfacing, targeted correction, and polishing techniques within one professional system—particularly useful when developing protocols for aging, pigmented, textured, and post-acne skin.

Engineered by Skin for Life for Precision Corrective Skin Resurfacing

The Nue Skin 100XL Professional Microdermabrasion Machine was designed and manufactured by Skin for Life, including its proprietary handpiece technology. Rather than adapting generic components, the system was engineered as a complete microdermabrasion platform in which the vacuum motor, crystal delivery system, and treatment handpieces work together to provide consistent crystal flow, controlled resurfacing, and exceptional treatment versatility. Each handpiece was developed with a specific clinical purpose, allowing experienced practitioners to tailor treatments according to skin condition, treatment goals, and anatomical location.

Blue Handpiece – Four-Port Ceramic Precision

The blue handpiece features Skin for Life’s proprietary four-port ceramic tip, engineered to provide balanced crystal dispersion across the treatment surface. The ceramic insert resists wear while promoting consistent crystal flow and uniform vacuum distribution throughout the procedure. This even dispersion helps create a smooth resurfacing pattern, making the handpiece well suited for full-face rejuvenation, photodamaged skin, and generalized skin texture refinement.

Red Handpiece – Focused Corrective Resurfacing

The red handpiece was engineered for practitioners performing advanced corrective skin resurfacing. Its concentrated crystal delivery and focused vacuum pattern provide enhanced precision for localized treatment areas with uneven skin texture, including the appearance of post-acne scarring and mature stretch marks. Designed for experienced providers, the red handpiece allows greater control when treating smaller, targeted areas that require more focused resurfacing.

Yellow Handpiece – Dynamic Pulsating Skin Retexturing

The yellow handpiece incorporates Skin for Life’s proprietary large-port DP Screw technology. This design creates a pulsating delivery of aluminum oxide crystals, natural polishing grains, or a customized blend of both media. The pulsating action continuously redistributes the resurfacing media, allowing practitioners to polish, refine, and retexture the skin while maintaining a smooth, controlled treatment pattern. The versatility of this handpiece enables providers to customize exfoliation based on individual skin conditions and treatment objectives.

An Integrated System Designed for Clinical Performance

Every component of the Nue Skin 100XL was engineered by Skin for Life to function as an integrated system rather than a collection of interchangeable parts. The relationship between the high-performance vacuum motor and the proprietary handpieces allows experienced practitioners to customize crystal flow, vacuum dynamics, and resurfacing intensity with greater precision. The result is a professional microdermabrasion platform designed for corrective skin resurfacing in medical spas, dermatology practices, plastic surgery centers, and advanced aesthetic clinics.

LSS™ delivery (Life Sustaining System)

Trademarked ingredient formulated for Skin for Life. LSS™ delivery is our exclusive Bio-emulsion nano-lipid technology. Our trademarked ingredients assist all skin colors, conditions and types by providing the best quality, innovation and superior bio-available ingredients. Our nano-lipid technology accelerates the effectiveness in ingredient absorption.

Learn more »

Skin for Life Microdermabrasion machines have options for additional add-on modailities.

LED Light Therapy Add-on $350.00, includes the choice of (2) lights RED or a RED and BLUE with (50) marketing rack cards.

Oxygen Infusion Skincare Add-on $200.00, includes all 5 products (ACE complex, antibacterial, brightening, sensitive, plus oxygen infusion activator phase 2) with airbrush, 16 Fl oz, and (50) marketing rack cards.

Sonic Skin Scrubber device and USB port $125.00, includes Sonic Skin Scrubber with USB cord, Papaya Complex enzyme exfoliant, and (50) marketing rack cards.

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Questions? Ask our Esthetician
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  • Reviews (2)

2 reviews for Nue Skin 100XL Microdermabrasion Machine

  1. Rated 5 out of 5

    Jo Ann Fenstermacher, CIDESCO Diplomat – January 10, 2019

    This is my go to miracle masque. I use the cryo algae & booster pack after full face waxing, lymphatic drainage, peels, microdermabrasion and dermaplaning. It really helps reduce the redness after any treatment and it leaves the skin cool, firm and tone. Also, I love this masque because it also reduces puffiness around the eyes. So when I am completed with my treatment, my guest can leave looking fresh and bright.

  2. Rated 5 out of 5

    Jo Ann Fenstermacher, CIDESCO Diplomat – January 10, 2019

    I am beyond impressed with the Oxygen Infusion Gel phase 1 sensitive + LSS™ delivery system. I first started using this after full facial waxing. Upon application, it immediately reduced the redness and reduce any discomfort my client might have from the hair removal. This oxygen treatment has turned a facial waxing into a relaxing spa experience. I also used it post peel, microdermabrasion and dermaplaning.

    In addition to reducing redness, it also leaves the skin feeling smooth and firm. And for the Floridian who has spent too much time in the sun, it also helped accelerate the healing and minimize the discomfort.

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