Price range: $199.00 through $2,999.00
*All equipment orders placed before 2pm EST require a 72 hour build time prior to shipping*
*For Licensed Skin Care or Medical Professionals Only*
The Nue Skin 500 is a professional microdermabrasion machine engineered for estheticians who want simple operation, consistent exfoliation, and long-lasting performance. Manufactured in the USA, this system supports both crystal and organic grain (finely milled walnut shell) microdermabrasion methods, making it a versatile choice for all skin types and treatment levels. Training and customer support are included with every purchase.
Key Features
Why Estheticians Choose the NUE Skin 500
Optional Upgrades (Add-Ons)
(Choose from dropdown menus on the product page.)
Upgrade your microdermabrasion treatments with Skin for Life’s professional Oxygen Infusion System. This add-on delivers a refreshing, cooling layer of oxygen to the skin, helping calm, hydrate, and support recovery immediately after exfoliation. Ideal for reducing redness and enhancing product penetration.
When you add the Oxygen Infusion System, you can also choose from our four targeted oxygen skincare concentrates:
A powerful antioxidant blend featuring vitamins A, C, and E to nourish, protect, and support skin vitality after microdermabrasion.
Formulated to help improve the appearance of dark spots and uneven tone while supporting a more radiant, balanced complexion.
Designed for breakout-prone or congested skin. Helps reduce surface bacteria and soothe post-treatment irritation for clearer, calmer results.
A calming, pH-balanced option ideal for reactive or delicate skin. Helps reduce redness and restore comfort after exfoliation.
Each oxygen treatment pairs with our Oxygen Infusion Activator, which enhances product absorption and delivers a smooth, cooling delivery of active ingredients.
Enhance your NUE Skin 500 system with Skin for Life’s LED Light Therapy Handpiece Add-On. Unlike panel-style LEDs that reflect or scatter light, our LED handpieces deliver direct skin contact, ensuring maximum absorption and stronger ATP responsiveness.
Our LED delivery method places the light source directly on the skin. This allows:
Precise, targeted delivery to specific treatment areas
Higher absorption of LED wavelengths
Minimal light loss or reflection
Stronger stimulation of mitochondrial activity
Better cell-to-cell communication for improved results
Direct-contact LED handpieces encourage a powerful ATP boost, helping support energy production within skin cells. This makes post-microdermabrasion treatments more effective, especially for rejuvenation, calming, and recovery.
Ideal for post-exfoliation calming
Supports collagen activity and healing
Enhances treatment outcomes with consistent, focused light
Great for small areas, spot treatments, and precision work
Skin for Life’s LED handpieces create a more controlled, intentional LED therapy experience perfectly complementing the professional microdermabrasion results delivered by the NUE Skin 500.
Trademarked ingredient formulated for Skin for Life. LSS™ delivery is our exclusive Bio-emulsion nano-lipid technology. Our trademarked ingredients assist all skin colors, conditions and types by providing the best quality, innovation and superior bio-available ingredients. Our nano-lipid technology accelerates the effectiveness in ingredient absorption.
Learn more »Note: Organic grains made from walnut shells are not recommended for clients with nut allergies.
ageless skincare system
Quantity of 50 Per Bag
active brighteners + LSS™ delivery
salicylic lactic citric + LSS™ delivery
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suebee731 –
I took delivery of my Nue Skin 500 a month ago and it is the best microdermabrasion machine I have owned. I have bought several in the past 20 years, and the performance of this machine is by far superior. From start to finish, the customer service, training and skin care products quality has been outstanding. I would recommend this machine to anyone seeking a well priced professional grade machine.
Skin for Life –
Thank you Sue for the kind words on our quality of machines, service, training and products. Skin for Life has been building microdermabrasion machines since 2003. Most are still being used today! With proper maintenance this machine should last you another 20 years making it the last microderm you will ever need!
Jo Ann Fenstermacher, CIDESCO Diplomat –
This is my go to miracle masque. I use the cryo algae & booster pack after full face waxing, lymphatic drainage, peels, microdermabrasion and dermaplaning. It really helps reduce the redness after any treatment and it leaves the skin cool, firm and tone. Also, I love this masque because it also reduces puffiness around the eyes. So when I am completed with my treatment, my guest can leave looking fresh and bright.
Jo Ann Fenstermacher, CIDESCO Diplomat –
I am beyond impressed with the Oxygen Infusion Gel phase 1 sensitive + LSS™ delivery system. I first started using this after full facial waxing. Upon application, it immediately reduced the redness and reduce any discomfort my client might have from the hair removal. This oxygen treatment has turned a facial waxing into a relaxing spa experience. I also used it post peel, microdermabrasion and dermaplaning.
In addition to reducing redness, it also leaves the skin feeling smooth and firm. And for the Floridian who has spent too much time in the sun, it also helped accelerate the healing and minimize the discomfort.